Your Data Worth More
Genetic data generated by your lab in the past, present, and future is your key asset. Owning this data enables efﬁcient analysis and interpretation, report generation, re-analysis of open cases, research and development, and the creation of new genetic tests, and will be key to your offering in the future.
Unlimited, Secure Data Management and Storage
Own and better monetize your genetic data
Geneyx provides your lab with an innovative, all-in-one platform for efﬁcient storage and management of all your genetic data, enabling you to maximize the value of your genetic data assets and guaranteeing a better future for your lab.
From raw sequencing data to automated comprehensive report generation Geneyx makes managing your data throughout your analysis workﬂow seamless. Your sequencing data, be it WGS, WES or small panels, ﬂows from your sequencing machine or provider directly into our platform, where we provide a one-stop-shop solution throughout the comprehensive reporting including integration with LIMS. Pipelines, workﬂows, reports and all genetic tests are fully customizable, enabling you to easily scale up your business while guaranteeing quality and consistency
Encrypted isolated and secure data storage
Geneyx is GDPR/HIPAA/CCPA ready, designed from the ground up to securely store genetic data. The data is stored safely, disconnected from the main cloud, and is never downloaded or transferred externally. The data is exclusively available through the Geneyx virtual environment, which enables a variety of data mining tools without compromising its anonymity and data security. This virtual environment also offers intra-lab and inter-lab extensive secure access controls and full auditing trails.
A novel, Knowledge-Driven NGS Interpretation & Reporting Platform
Rapid analysis and interpretation with a higher diagnostic yield
‘Geneyx Analysis’ is a novel, knowledge-driven Next Generation Sequencing (NGS) analysis, interpretation and reporting engine, which leverages the popular GeneCards Knowledgebase suite . It enables rapid diagnosis of causal mutations, collecting clinical and molecular information from >120 data sources, and prioritizing variants based on their association with patients’ exhibited phenotypes. ‘Geneyx analysis’ engine, offers market-leading diagnostic yields (above 50% in rare disorders on WES) and reduced turnaround time from hours or days to minutes . Built for the future of genomic analysis, it offers best-in-class phenotype-driven structural and copy number variation interpretation on coding and regulatory regions . To date, ‘Geneyx analysis’ and the GeneCards suite have helped in the analysis of tens of thousands of clinical genetic cases world-wide.
Beneﬁts and Features
• Best-of-breed scoring and prioritization of variants based on association with disease/phenotypes of interest 
• Comprehensive evidence for each association for the evaluation of variants and- reporting
• Leverages the extensive data available in the GeneCards Suite Knowledgebase 
• Supports free-text searching for phenotypes, as well as direct and indirect gene-phenotype relationships 
• Designed for single samples, trios and pedigree trees (incl. integrated compound heterozygous analysis) 
• Best-in-class phenotype-driven structural and copy number variation interpretation on coding and regulatory regions 
References 1. Stelzer G, Rosen N, Plaschkes I et al. The GeneCards Suite: From Gene Data Mining to Disease Genome Sequence Analyses. Curr Protoc Bioinformatics (2016) 2. Dahary, D, Golan, Y, Mazor Y et al. Genome analysis and knowledge-driven variant interpretation with TGex. BMC Med Genomics (2019). 3. Suwinski P, Ong C, Ling MHT et al. Advancing Personalized Medicine Through the Application of Whole Exome Sequencing and Big Data Analytics. Frontiers in Genetics (2019) 4. Stelzer G, Plaschkes I, Oz-Levi D et al. VarElect: the phenotype-based variation prioritizer of the GeneCards Suite. BMC Genomics (2016)
Better Monetization For Your Genetic Data
More revenue opportunities with ‘Off the shelf’ Genetic applications
Newmarket opportunities can be immediately addressed using our numerous off-the-shelf CLIA/CAP-clinically ready tests and reports with a click of a button, that is fully white-labeled for your organization. Maximize your existing genetic data by providing valuable, actionable ﬁndings to your customers with previously sequenced samples. Geneyx makes it easy to identify new opportunities for genetic tests, which allows you to generate more revenues with higher margins
Highlights of the Geneyx Apps – predeﬁned tests
Harness our powerful cloud-based data storage and genome engine to perform singleton, trio, or population-based analysis. Select from numerous CLIA/CAP accredited tests/reports with a click of a button! No additional set-up, validation, or work required to offer these tests/reports “right off the shelf”. Convert your research samples to clinical tests/reports in a matter of minutes and provide valuable actionable ﬁndings to the test subjects of your previously sequenced samples. Drive untapped sources of revenue to your lab, or organization with these CLIA/CAP clinical ready tests/reports.
Select from our comprehensive portfolio, including:
• Comprehensive DNA UNLOCKED® test/report providing the most complete screening and reporting of your patient’s or research subject’s exome or genome data
• Cancer Predisposition
• Carrier Screening
• Rare Disease/Gene Discovery
• Cardiovascular Disease
• Nutrition/Fitness and Wellness
• Substance Use Disorders
• Metabolic Disorders
• Additional custom tests/reports by Geneyx Apps based on your requirements