Personalized Nutrition & Fitness

Test Information Sheet

Microarray

 

Description:

Today we are learning more and more about the interaction of our diet, exercise, and other lifestyle habits with our genetics and how it may affect our health and wellness. With the Personalized Nutrition & Fitness Genome test, we analyzed and interpret vital parts of an individual’s genome to give insights about their nutrition and fitness traits, as well as some additional traits and ancestry. With this knowledge the test subject and his or her healthcare providers, dieticians/nutritionists or fitness trainers could personalize their diet or fitness routine.

 

Microarray allows for the genotyping of specific variations or polymorphisms associated with cardiovascular conditions in the genome of an individual. It is different from WES in that specific variants are targeted either within the protein-coding regions or in the non-coding regions of the genome.

 

Test Method:

Genotyping method of DNA is done using Illumina iScan technology to capture regions of the genome that are within (i.e. exonic) and outside of the protein coding genes (i.e. intergenic). SNPs (Single Nucleotide Polymorphisms) or variants from the microarray data are used in the analysis to generate parts of this report. The genotyping of the data is performed at the Gene by Gene, Ltd. laboratory located in 1445 North Loop West, Suite 760 Houston, TX 77008. Analysis, interpretation and report is performed by TOVANA HEALTH located at 945 McKinney St. Suite# 11977 Houston, TX 77002.

 

Limitations:

Absence of a causative variant(s) or SNPs (Single Nucleotide Polymorphisms) related to a trait by data obtained from microarray method does not exclude a genetic basis of the individual’s condition/trait. Some types of genetic abnormalities may not be detectable with the technologies utilized for this testing. This test does not analyze mitochondrial DNA sequence or epigenetic changes of the genome. It is possible that the genomic region where a variant contributing to the trait/condition exists in the individual tested was not captured or accurately mapped to the reference sequence using the current technologies and therefore was not detected. Additionally, it is possible that a particular genetic change may not be recognized as the underlying cause of the trait due to incomplete scientific knowledge about the function of all genes in the human genome and the impact of variations in those genes. Variants in genes associated with the trait or thought to potentially relevant for the individual’s analysis are included in this report. It should be noted that the heritability (i.e. the proportion that genetic variation contributes to the variance of a phenotypic trait) is only partial (< 100%) for the traits being analyzed. Lifestyle and other environmental factors contribute the variance of the trait as well and should be accounted for when interpreting these results. Variants or SNPs in genes associated with various traits related to nutrition, fitness, and additional traits are included in this report (Table 1).

 

Table 1 – List of traits Included in the test

 

Category/Section Traits
Nutrition  

Cardiometabolic Health

·        Caffeine Metabolism

·        Type 2 Diabetes Risk / Whole Grains & Fiber Benefits

·        Omega-3 and Omega-6 Levels

 

Food Reactions & Taste Perception

·        Lactose Intolerance

·        Bitter Taste Perception

 

Nutritional Needs & Nutrition Metabolism

·        Vitamin B2 (Riboflavin)

·        Vitamin B12 (Cobalamin)

·        Vitamin C (Ascorbic Acid)

 

Fitness

 

·        Exercise Behavior

·        Power and Strength

·        Endurance / Endurance Training

·        Pain Sensitivity

·        Achilles Tendon Injury / Tendinopathy

·        Muscle Fatigue & Cramping

·        Aerobic Capacity (VO2max)

·        Blood Pressure Response to Exercise

·        Weight – BMI Response to Exercise

Additional Traits  

·        Wet vs. Dry Earwax, Sweating and Body Odor

·        Hair Loss and Baldness (Androgenic Alopecia)

·        Dental Caries

·        Sleep Depth (Deep Sleep)

Ancestry Genetics (optional)  

Family ancestry

·        Discover the percentage breakdown of your origins

·        Connect with your autosomal DNA relatives within the last 5 generations

·        Learn if you have a connection with ancient European groups

·        Compare matching segments of DNA (blocks) with your genetic matches

 

 

Ordering:

CATALOG NUMBER: 1100113, 1197213, 1100013
TURNAROUND TIME: 2-4 weeks
PREFERRED SPECIMEN: Buccal swab
ALTERNATIVE SPECIMEN:  

Extracted DNA: 20ul of 50ng/ul, OD260/OD280 ~ 1.8, include details of extraction method with samples

 

Blood: 3-5cc drawn in EDTA (purple-top) tube